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Anti-VDAC1/Porin Rabbit Monoclonal Antibody

Boster Bio Anti-VDAC1/Porin Rabbit Monoclonal Antibody catalog # M01168. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Voltage-dependent anion-selective channel protein 1; VDAC-1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; VDAC1; VDAC

Gene Name

VDAC1

Gene ID

7416

UniProt

P21796

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human VDAC1

Clonality

Monoclonal

Clone

Clone: DBA-22

Tissue Specificity

Heart, liver and skeletal muscle.

Applications

WB, IHC, ICC, IF

Field of Research

Subcellular Markers, Tags & Cell Markers

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

30773 MW

Observed Molecular Weight

48 kDa

Gene Name Synonym

Voltage-dependent anion-selective channel protein 1

Subcellular Location

Mitochondrion outer membrane . Cell membrane .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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