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Anti-MMP12 Rabbit Monoclonal Antibody

Boster Bio Anti-MMP12 Rabbit Monoclonal Antibody catalog # M01520. Tested in WB application. This antibody reacts with Human.

Product Specifications

Synonyms

Macrophage metalloelastase; MME;3.4.24.65; Macrophage elastase; ME; hME; Matrix metalloproteinase-12; MMP-12; MMP12; HME

Gene Name

MMP12

Gene ID

4321

UniProt

P39900

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human MMP12

Clonality

Monoclonal

Clone

Clone: CHE-13

Tissue Specificity

Found in alveolar macrophages but not in peripheral blood monocytes.

Applications

WB

Field of Research

Angiogenesis, Atherosclerosis, Cancer, Cardiovascular, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Signal Transduction, Tumor Biomarkers

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

54002 MW

Observed Molecular Weight

43 kDa

Gene Name Synonym

Macrophage metalloelastase

Subcellular Location

Secreted, extracellular space, extracellular matrix .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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