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Anti-Smad1 Rabbit Monoclonal Antibody

Boster Bio Anti-Smad1 Rabbit Monoclonal Antibody catalog # M00728-1. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein 1; BSP-1; SMAD1; BSP1, MADH1, MADR1

Gene Name

SMAD1

Gene ID

4086

UniProt

Q15797

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human Smad1

Clonality

Monoclonal

Clone

Clone: CAC-19

Tissue Specificity

Ubiquitous. Highest expression seen in the heart and skeletal muscle.

Applications

WB, ICC, IF

Field of Research

Growth Factors, Metabolism, Metabolism Processes, Nuclear Signaling, Nuclear Signaling Pathways, Pathways and Processes, Response To Hypoxia, Signal Transduction, Signaling Pathway, Stem Cells, TGF Beta

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) . SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP) -mediated cardiac-specific gene expression. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

52260 MW

Observed Molecular Weight

90 kDa

Gene Name Synonym

Mothers against decapentaplegic homolog 1

Subcellular Location

Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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