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Anti-c-Jun Rabbit Monoclonal Antibody

Boster Bio Anti-c-Jun Rabbit Monoclonal Antibody catalog # M02038. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39; JUN

Gene Name

JUN

Gene ID

3725

UniProt

P05412

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human c-Jun

Clonality

Monoclonal

Clone

Clone: CAO-10

Tissue Specificity

Expression is restricted to melanoma and melanocyte cell lines and retina.

Applications

WB, IHC, ICC, IF, IP

Field of Research

Hlh/Leucine Zipper, Immunology, Innate Immunity, Nuclear Signaling Pathways, Oncoproteins, Oncoproteins/Suppressors, Signal Transduction, Signaling Pathway, TLR Signaling, Transcription, Transcription Factors

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306) . Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

35676 MW

Observed Molecular Weight

43 kDa

Gene Name Synonym

Transcription factor AP-1

Subcellular Location

Nucleus.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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