Anti-Smad2 Rabbit Monoclonal Antibody

Boster Bio Anti-Smad2 Rabbit Monoclonal Antibody catalog # M00090-1. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Mothers against decapentaplegic homolog 2; MAD homolog 2; Mothers against DPP homolog 2; JV18-1; Mad-related protein 2; hMAD-2; SMAD family member 2; SMAD 2; Smad2; hSMAD2; SMAD2; MADH2, MADR2

Gene Name

SMAD2

Gene ID

4087

UniProt

Q15796

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Smad2

Clonality

Monoclonal

Clone

Clone: ACI-19

Tissue Specificity

Expressed at high levels in skeletal muscle, endothelial cells, heart and placenta. .

Applications

WB, ICC, IF, Flow Cytometry

Field of Research

Growth Factors, Nuclear Signaling, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway, Stem Cells, TGF Beta

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

52306 MW

Observed Molecular Weight

52 kDa

Gene Name Synonym

Mothers against decapentaplegic homolog 2

Subcellular Location

Cytoplasm. Nucleus. Cytoplasmic and nuclear in the absence of TGF-beta. On TGF-beta stimulation, migrates to the nucleus when complexed with SMAD4. On dephosphorylation by phosphatase PPM1A, released from the SMAD2/SMAD4 complex, and exported out of the nucleus by interaction with RANBP1.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS8299746-01 5 nmol

hsa-miR-4793-3p miRNA Mimic

Ask

View Details

MBS8299746-02 10 nmol

hsa-miR-4793-3p miRNA Mimic

Ask

View Details

MBS8299746-03 5x 10 nmol

hsa-miR-4793-3p miRNA Mimic

Ask

View Details

GTR15300978 1 Vial

Lentiviral mouse Oscar shRNA (UAS) - Lentiviral mouse Oscar shRNA (UAS, iRFP) (100)

Ask

View Details

MBS280916-01 48 Tests

Human Potassium voltage-gated channel subfamily H member 2 (KCNH2) ELISA Kit

Ask

View Details

MBS280916-02 96 Tests

Human Potassium voltage-gated channel subfamily H member 2 (KCNH2) ELISA Kit

Ask

View Details

Anti-Smad2 Rabbit Monoclonal Antibody

Product Specifications

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Immunogen

Clonality

Clone

Tissue Specificity

Applications

Field of Research

Purification

Concentration

Form

Function

Storage Conditions

Calculated Molecular Weight

Observed Molecular Weight

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

Explore Other Products

hsa-miR-4793-3p miRNA Mimic

hsa-miR-4793-3p miRNA Mimic

hsa-miR-4793-3p miRNA Mimic

Lentiviral mouse Oscar shRNA (UAS) - Lentiviral mouse Oscar shRNA (UAS, iRFP) (100)

Human Potassium voltage-gated channel subfamily H member 2 (KCNH2) ELISA Kit

Human Potassium voltage-gated channel subfamily H member 2 (KCNH2) ELISA Kit