Anti-Bcl-2 Rabbit Monoclonal Antibody
Anti-Bcl-2
Product Specifications
Synonyms
Apoptosis regulator Bcl-2; BCL2
Gene Name
BCL2
Gene ID
596
UniProt
P10415
Host
Rabbit
Reactivity
Human
Immunogen
A synthesized peptide derived from human Bcl-2
Clonality
Monoclonal
Clone
Clone: HF-2
Tissue Specificity
Expressed in a variety of tissues.
Applications
WB, IHC, ICC, IF, IP, Flow Cytometry
Field of Research
Oncoproteins, Oncoproteins/Suppressors, Pathways and Processes, Response To Hypoxia, Signal Transduction, Tumor Biomarkers
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) . .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
26266 MW
Observed Molecular Weight
83, 88 kDa
Gene Name Synonym
Apoptosis regulator Bcl-2
Subcellular Location
Mitochondrion outer membrane ; Single-pass membrane protein . Nucleus membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein .
Protein Name
P2X purinoceptor 1
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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