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Anti-GDNF Rabbit Monoclonal Antibody

Boster Bio Anti-GDNF Rabbit Monoclonal Antibody catalog # M00710. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Glial cell line-derived neurotrophic factor; hGDNF; Astrocyte-derived trophic factor; ATF; GDNF

Gene Name

GDNF

Gene ID

2668

UniProt

P39905

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human GDNF

Clonality

Monoclonal

Clone

Clone: ABDB-7

Tissue Specificity

In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change. .

Applications

WB, Flow Cytometry

Field of Research

Developmental Biology, Growth and Development, Neurodegenerative Disease, Neurology Process, Neuroscience, Organogenesis

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

23720 MW

Observed Molecular Weight

28 kDa

Gene Name Synonym

Glial cell line-derived neurotrophic factor

Subcellular Location

Secreted .

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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