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Anti-SOS1 Rabbit Monoclonal Antibody

Boster Bio Anti-SOS1 Rabbit Monoclonal Antibody catalog # M00837. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Son of sevenless homolog 1; SOS-1; SOS1

Gene Name

SOS1

Gene ID

6654

UniProt

Q07889

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human SOS1

Clonality

Monoclonal

Clone

Clone: ABBE-19

Tissue Specificity

Expressed in gingival tissues. .

Applications

WB, IHC, ICC, IF

Field of Research

Cancer, G Protein Signaling, Ras Family, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579) . Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331) . Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

152464 MW

Observed Molecular Weight

68 kDa

Gene Name Synonym

Son of sevenless homolog 1

Subcellular Location

Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with NEK6 in the centrosome.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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