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Anti-CD18 ITGB2 Rabbit Monoclonal Antibody

Boster Bio Anti-CD18 ITGB2 Rabbit Monoclonal Antibody catalog # M00458. Tested in WB, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD18; ITGB2; CD18, MFI7

Gene Name

ITGB2

Gene ID

3689

UniProt

P05107

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CD18

Clonality

Monoclonal

Clone

Clone: AAIH-9

Tissue Specificity

Highly expressed in placenta. Low expression in small intestine, liver and colon. .

Applications

WB, IP

Field of Research

Cell Adhesion, Cell Type Markers, Cytoskeleton/ECM, Hematopoietic Progenitors, Immunology, Integrins, Myeloid, Signal Transduction, Stem Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha- D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

84782 MW

Observed Molecular Weight

73 kDa

Gene Name Synonym

Integrin beta-2

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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