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Anti-CD59 Rabbit Monoclonal Antibody

Boster Bio Anti-CD59 Rabbit Monoclonal Antibody catalog # M00914-1. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

CD59 glycoprotein;1F5 antigen;20 kDa homologous restriction factor; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP; MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; Protectin; CD59; CD59; MIC11, MIN1, MIN2, MIN3, MSK21

Gene Name

CD59

Gene ID

966

UniProt

P13987

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CD59

Clonality

Monoclonal

Clone

Clone: AABE-3

Tissue Specificity

Detected in caudate, nucleus accumbens and in the olfactory tubercle. .

Applications

WB, ICC, IF, IP, Flow Cytometry

Field of Research

Atherosclerosis, Cardiovascular, Cell Type Markers, Complement, Hematopoietic Progenitors, Immunology, Innate Immunity, Protein Phosphorylation, Signal Transduction, Stem Cells, Surface Molecules, Tyrosine Kinases, Vascular Inflammation

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

14177 MW

Observed Molecular Weight

120 kDa

Gene Name Synonym

CD59 glycoprotein

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Soluble form found in a number of tissues.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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