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Anti-BMP2 Rabbit Monoclonal Antibody

Boster Bio Anti-BMP2 Rabbit Monoclonal Antibody catalog # M00338. Tested in WB application. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A; BMP2; BMP2A

Gene Name

BMP2

Gene ID

650

UniProt

P12643

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human BMP2

Clonality

Monoclonal

Clone

Clone: AOHD-2

Tissue Specificity

Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.

Applications

WB

Field of Research

Angiogenesis, Cancer, Cardiovascular, Cytoskeleton/ECM, Extracellular Matrix, Growth Factors, Growth Factors/Hormones, Neural Stem Cells, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, Structures, TGF Beta

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Induces cartilage and bone formation (PubMed:3201241) . Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

44702 MW

Observed Molecular Weight

32 kDa

Gene Name Synonym

Bone morphogenetic protein 2

Subcellular Location

Secreted.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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