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Anti-KLF4/Gklf Rabbit Monoclonal Antibody

Boster Bio Anti-KLF4/Gklf Rabbit Monoclonal Antibody catalog # M00120. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Krueppel-like factor 4; Epithelial zinc finger protein EZF; Gut-enriched krueppel-like factor; KLF4; EZF, GKLF

Gene Name

KLF4

Gene ID

9314

UniProt

O43474

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human KLF4

Clonality

Monoclonal

Clone

Clone: AODA-11

Tissue Specificity

Highly expressed in heart, placenta, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis and peripheral blood.

Applications

WB, IHC, ICC, IF

Field of Research

Cancer, Cardiovascular, Cell Cycle, Cell Cycle Inhibitors, Cell Differentiation, Developmental Biology, Domain Families, Embryogenesis, Embryonic Stem Cells, Epigenetics and Nuclear Signaling, Hypertrophy, Intracellular, Krueppel Like Factor, Oncoproteins, Oncoproteins/Suppressors, Stem Cells, Surface Molecules, Transcription, Transcription Factors, Tumor Suppressors

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

54671 MW

Observed Molecular Weight

70 kDa

Gene Name Synonym

Krueppel-like factor 4

Subcellular Location

Nucleus.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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