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Anti-Bmi1 Rabbit Monoclonal Antibody

Boster Bio Anti-Bmi1 Rabbit Monoclonal Antibody catalog # M00313. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51; BMI1; PCGF4, RNF51

Gene Name

BMI1

Gene ID

648

UniProt

P35226

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A synthesized peptide derived from human Bmi1

Clonality

Monoclonal

Clone

Clone: IHE-2

Tissue Specificity

Ubiquitously expressed in various human primary cells and tumor cell lines. .

Applications

WB, IHC, ICC, IF

Field of Research

Cancer, Cancer Susceptibility, Cell Biology, Cell Cycle, Cell Differentiation,2339, Chromatin Remodeling, Epigenetics and Nuclear Signaling, Hematopoietic Progenitors, Oncoproteins, Oncoproteins/Suppressors, Proto-Oncogenes, Stem Cells, Transcription

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

36949 MW

Observed Molecular Weight

40 kDa

Gene Name Synonym

Polycomb complex protein BMI-1

Subcellular Location

Nucleus. Cytoplasm.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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