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Anti-ATF1 Rabbit Monoclonal Antibody

Boster Bio Anti-ATF1 Rabbit Monoclonal Antibody catalog # M01600. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1; Protein TREB36; ATF1

Gene Name

ATF1

Gene ID

466

UniProt

P18846

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human ATF1

Clonality

Monoclonal

Clone

Clone: HBF-1

Tissue Specificity

Ubiquitously expressed, with highest levels in prostate, pancreas and kidney (PubMed:14615060, PubMed:15496141, PubMed:19664597) . Expressed in melanocytes (PubMed:23999003) . .

Applications

WB, ICC, IF, IP

Field of Research

Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Transcription

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

29233 MW

Observed Molecular Weight

92 kDa

Gene Name Synonym

Cyclic AMP-dependent transcription factor ATF-1

Subcellular Location

Nucleus.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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