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Anti-Oct4 POU5F1 Rabbit Monoclonal Antibody

Selected Variant

M00174

Size: 100 µL/Vial

Boster Bio Anti-Oct4 POU5F1 Rabbit Monoclonal Antibody catalog # M00174. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

POU domain, class 5, transcription factor 1; Octamer-binding protein 3; Oct-3; Octamer-binding protein 4; Oct-4; Octamer-binding transcription factor 3; OTF-3; POU5F1; OCT3, OCT4, OTF3

Gene Name

POU5F1

Gene ID

5460

UniProt

Q01860

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human Oct4

Clonality

Monoclonal

Clone

Clone: GDI-16

Tissue Specificity

Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues. .

Applications

WB, IHC, ICC, IF, IP

Field of Research

Chromatin Binding Proteins, Developmental Families, DNA/RNA Binding, Domain Families, Epigenetics and Nuclear Signaling, Transcription, Transcription Factors

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') . Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

38571 MW

Observed Molecular Weight

29 kDa

Gene Name Synonym

POU domain, class 5, transcription factor 1

Subcellular Location

Cytoplasm. Nucleus. Expressed in a diffuse and slightly punctuate pattern.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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