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Anti-DKK1 Rabbit Monoclonal Antibody

Boster Bio Anti-DKK1 Rabbit Monoclonal Antibody catalog # M00632. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK; DKK1; UNQ492/PRO1008

Gene Name

DKK1

Gene ID

22943

UniProt

O94907

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A synthesized peptide derived from human DKK1

Clonality

Monoclonal

Clone

Clone: FHG-4

Tissue Specificity

Placenta.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Cardiovascular, Developmental Biology, Embryogenesis, Immunology, Secreted, Signaling Pathways, Stem Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

28672 MW

Observed Molecular Weight

26 kDa

Gene Name Synonym

Dickkopf-related protein 1

Subcellular Location

Secreted.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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