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Anti-COX1 PTGS1 Rabbit Monoclonal Antibody

Boster Bio Anti-COX1 PTGS1 Rabbit Monoclonal Antibody catalog # M00811. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Prostaglandin G/H synthase 1;1.14.99.1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1; PTGS1; COX1

Gene Name

PTGS1

Gene ID

5742

UniProt

P23219

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human COX1

Clonality

Monoclonal

Clone

Clone: FHF-16

Tissue Specificity

CNS stem cells.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Atherosclerosis, Cancer, Cancer Metabolism, Cardiovascular, Endocrine Metabolism, Heart Disease, Hormone Biosynthesis, Immunology, Innate Immunity, Lipid and Lipoprotein Metabolism, Lipid Signaling, Macrophage/Inflammation, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Oxidative Stress, Pathways and Processes, Platelets, Redox Metabolism, Signal Transduction, Signaling Pathway

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

68686 MW

Observed Molecular Weight

180 kDa

Gene Name Synonym

Prostaglandin G/H synthase 1

Subcellular Location

Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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