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Anti-PUMA BBC3 Rabbit Monoclonal Antibody

Boster Bio Anti-PUMA BBC3 Rabbit Monoclonal Antibody catalog # M04899. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis; BBC3; PUMA

Gene Name

BBC3

Gene ID

27113

UniProt

Q9BXH1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human PUMA

Clonality

Monoclonal

Clone

Clone: DDO-2

Tissue Specificity

Ubiquitously expressed. .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Apoptosis, Apoptotic Markers, Cancer, Cell Biology, Cell Death, Intracellular, Invasion/Microenvironment, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Pathways and Processes, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Essential mediator of p53/TP53-dependent and p53/TP53- independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

20532 MW

Observed Molecular Weight

21 kDa

Gene Name Synonym

Bcl-2-binding component 3

Subcellular Location

Mitochondrion . Localized to the mitochondria in order to induce cytochrome c release.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

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