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Anti-CD86/B7 2 Rabbit Monoclonal Antibody

Boster Bio Anti-CD86/B7 2 Rabbit Monoclonal Antibody catalog # M00220-1. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD86; CD86; CD28LG2

Gene Name

CD86

Gene ID

942

UniProt

P42081

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human CD86

Clonality

Monoclonal

Clone

Clone: BFF-3

Tissue Specificity

Expressed by activated B-lymphocytes and monocytes.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Adaptive Immunity, Cell Type Markers, Hematopoietic Progenitors, Host-Virus Interaction, Immunology, Interspecies Interaction, Lymphoid, Microbiology, Myeloid, Stem Cells, T Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T- cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

37682 MW

Observed Molecular Weight

70 kDa

Gene Name Synonym

T-lymphocyte activation antigen CD86

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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