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Anti-Nrf2 NFE2L2 Rabbit Monoclonal Antibody

Boster Bio Anti-Nrf2 NFE2L2 Rabbit Monoclonal Antibody catalog # M00078. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2; NFE2L2; NRF2

Gene Name

NFE2L2

Gene ID

4780

UniProt

Q16236

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human Nrf2

Clonality

Monoclonal

Clone

Clone: AGH-14

Tissue Specificity

Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle.

Applications

WB, IHC, ICC, IF, IP

Field of Research

Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Metabolic Signaling Pathways, Metabolism, Mitochondrial Metabolism, Nucleotide Metabolism, Oxidative Stress, Pathways and Processes, Redox Metabolism, Transcription

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

67827 MW

Observed Molecular Weight

70 kDa

Gene Name Synonym

Nuclear factor erythroid 2-related factor 2

Subcellular Location

Cytoplasm, cytosol. Nucleus. Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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