Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-DCX/Doublecortin Rabbit Monoclonal Antibody

Boster Bio Anti-DCX/Doublecortin Rabbit Monoclonal Antibody catalog # M01053. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Neuronal migration protein doublecortin; Doublin; Lissencephalin-X; Lis-X; DCX; DBCN, LISX

Gene Name

DCX

Gene ID

1641

UniProt

O43602

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human DCX

Clonality

Monoclonal

Clone

Clone: AOAD-4

Tissue Specificity

Highly expressed in neuronal cells of fetal brain (in the majority of cells of the cortical plate, intermediate zone and ventricular zone), but not expressed in other fetal tissues. In the adult, highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas.

Applications

WB, Flow Cytometry

Field of Research

Cancer, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

40574 MW

Observed Molecular Weight

45 kDa

Gene Name Synonym

Neuronal migration protein doublecortin

Subcellular Location

Cytoplasm. Cell projection . Localizes at neurite tips. .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Recombinant Human UBE4B Protein
E30P6533 20 µg

Recombinant Human UBE4B Protein

Ask
View Details
Frizzled homolog 1 (FZD1) Human shRNA Plasmid Kit (Locus ID 8321)
TL312886 1 Kit

Frizzled homolog 1 (FZD1) Human shRNA Plasmid Kit (Locus ID 8321)

Ask
View Details
Recombinant Human ZNF236 Protein
E30P2910 20 µg

Recombinant Human ZNF236 Protein

Ask
View Details
Mir106a Mouse qPCR Template Standard (MI0000406)
MK300023 200 Reactions

Mir106a Mouse qPCR Template Standard (MI0000406)

Ask
View Details
Recombinant Human ESM1 Protein, His, E.coli-1mg
QP11810-HIS-EC-1mg 1mg

Recombinant Human ESM1 Protein, His, E.coli-1mg

Ask
View Details
Human Apolipoprotein E (APOE) ELISA Kit
MBS454269-01 48 Tests

Human Apolipoprotein E (APOE) ELISA Kit

Ask
View Details