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Anti-Phospho-B Raf (T401) Rabbit Monoclonal Antibody

Boster Bio Anti-Phospho-B Raf (T401) Rabbit Monoclonal Antibody catalog # P00075. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Phospho Site

T401

Synonyms

Serine/threonine-protein kinase B-raf;2.7.11.1; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1, RAFB1

Gene Name

BRAF

Gene ID

673

UniProt

P15056

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Phospho-B Raf (T401)

Clonality

Monoclonal

Clone

Clone: IBE-2

Tissue Specificity

Brain and testis.

Applications

WB, ICC, IF, IP

Field of Research

Cancer Metabolism, Cytoplasmic, Epigenetics and Nuclear Signaling, Metabolism, Metabolism Processes, Nuclear Signaling, Nuclear Signaling Pathways, Pathways and Processes, Response To Hypoxia, Signal Transduction, Signaling Pathway, Stem Cells, TGF Beta

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

84437 MW

Observed Molecular Weight

90-100 kDa

Gene Name Synonym

Serine/threonine-protein kinase B-raf

Subcellular Location

Nucleus . Cytoplasm. Cell membrane . Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes. .

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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