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Anti-Phospho-Hsp27 (S78) HSPB1 Rabbit Monoclonal Antibody

Boster Bio Anti-Phospho-Hsp27 (S78) HSPB1 Rabbit Monoclonal Antibody catalog # P00676. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Product Specifications

Phospho Site

S78

Synonyms

Heat shock protein beta-1; HspB1;28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27; HSPB1; HSP27, HSP28

Gene Name

HSPB1

Gene ID

3315

UniProt

P04792

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Phospho-Hsp27 (S78)

Clonality

Monoclonal

Clone

Clone: IBC-8

Tissue Specificity

Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle. .

Applications

WB, IHC, ICC, IF, IP

Field of Research

Atherosclerosis, Cancer, Cardiovascular, Chaperones, Contractility, Heat Shock Proteins, Protein Trafficking, Signal Transduction, Tumor Biomarkers

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Involved in stress resistance and actin organization.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

22783 MW

Observed Molecular Weight

185 kDa

Gene Name Synonym

Heat shock protein beta-1

Subcellular Location

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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