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Anti-Phospho-Creb (S133) CREB1 Rabbit Monoclonal Antibody

Boster Bio Anti-Phospho-Creb (S133) CREB1 Rabbit Monoclonal Antibody catalog # P00577-1. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Phospho Site

S133

Synonyms

Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1; CREB1

Gene Name

CREB1

Gene ID

12912

UniProt

P16220

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Phospho-Creb (S133)

Clonality

Monoclonal

Clone

Clone: IG-3

Tissue Specificity

Highly expressed in testis and placenta. Low levels in bronchial epithelial cells. .

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Transcription, Transcription Factors

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

36688 MW

Observed Molecular Weight

185 kDa

Gene Name Synonym

Cyclic AMP-responsive element-binding protein 1

Subcellular Location

Nucleus .

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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