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Anti-Phospho-Tyrosine Rabbit Monoclonal Antibody

Boster Bio Anti-Phospho-Tyrosine Rabbit Monoclonal Antibody catalog # PT0005. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Histone H2A.2; HTA2; H2A2; YBL003C; YBL0103

Gene Name

Tyrosine

Gene ID

852283

UniProt

P04912

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from Phosphotyrosine

Clonality

Monoclonal

Clone

Clone: AAOI-20

Tissue Specificity

Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

Applications

WB, ICC, IF, IP, Flow Cytometry

Field of Research

Epigenetics and Nuclear Signaling, Histones

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

13989 MW

Observed Molecular Weight

140 kDa, 130 kDa, 110 kDa

Gene Name Synonym

Histone H2A.2

Subcellular Location

Nucleus. Chromosome.

Protein Name

Synapsin-1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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