Anti-GSK3 beta Rabbit Monoclonal Antibody
Anti-GSK3 beta Rabbit Monoclonal Antibody
Product Specifications
Synonyms
Glycogen synthase kinase-3 beta; GSK-3 beta;2.7.11.26; Xgsk-3 protein; gsk3b; Xgsk-3
Gene Name
GSK3B
Gene ID
2932
UniProt
P49841
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human GSK3 beta
Clonality
Monoclonal
Clone
Clone: EB-7
Tissue Specificity
Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Colocalizes with EIF2AK2/PKR and TAU in the Alzheimer disease (AD) brain.
Applications
WB, IHC, ICC, IF, Flow Cytometry
Field of Research
Carbohydrate Metabolism, Cell Biology, Cell Cycle, Cell Differentiation, Developmental Biology, Energy Metabolism, Metabolic Signaling Pathways, Metabolism, Nervous System Development, Neurogenesis, Neurology Process, Neuroscience, Organogenesis, Pathways and Processes, Signal Transduction
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Plays a role in the organization of the formation of the main body axis of developing embryo. Acts as an inhibitor of differentiation of primary neurons. Inhibits the ability of ectopically expressed NEUROD1 and other bHLH factors to promote early retinal cell differentiation. May participate in the Wnt signaling pathway. May regulate the circadian clock via phosphorylation of the major clock components. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
47 kDa
Observed Molecular Weight
47 kDa
Gene Name Synonym
Glycogen synthase kinase-3 beta
Subcellular Location
Cytoplasm . Nucleus . Cell membrane .
Protein Name
Glycogen synthase kinase-3 beta (gsk3b)
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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