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Anti-GSK3 beta Rabbit Monoclonal Antibody

Anti-GSK3 beta Rabbit Monoclonal Antibody

Product Specifications

Synonyms

Glycogen synthase kinase-3 beta; GSK-3 beta;2.7.11.26; Xgsk-3 protein; gsk3b; Xgsk-3

Gene Name

GSK3B

Gene ID

2932

UniProt

P49841

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human GSK3 beta

Clonality

Monoclonal

Clone

Clone: EB-7

Tissue Specificity

Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Colocalizes with EIF2AK2/PKR and TAU in the Alzheimer disease (AD) brain.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Carbohydrate Metabolism, Cell Biology, Cell Cycle, Cell Differentiation, Developmental Biology, Energy Metabolism, Metabolic Signaling Pathways, Metabolism, Nervous System Development, Neurogenesis, Neurology Process, Neuroscience, Organogenesis, Pathways and Processes, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Plays a role in the organization of the formation of the main body axis of developing embryo. Acts as an inhibitor of differentiation of primary neurons. Inhibits the ability of ectopically expressed NEUROD1 and other bHLH factors to promote early retinal cell differentiation. May participate in the Wnt signaling pathway. May regulate the circadian clock via phosphorylation of the major clock components. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

47 kDa

Observed Molecular Weight

47 kDa

Gene Name Synonym

Glycogen synthase kinase-3 beta

Subcellular Location

Cytoplasm . Nucleus . Cell membrane .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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