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Anti-Ras-related protein Rab-3C Rab3C Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Ras-related protein Rab-3C is a protein that in humans is encoded by the RAB3C gene. It is mapped to 5q11.2. RAB3C is found in brain, adrenal gland and pituitary. This gene is one of the small GTPases implicated in the regulation of vesicular trafficking between membrane compartments. RAB3C gene contains 6 exons and spans more than 310 kb. The function of this gene is transporting protein, and probably involved in vesicular traffic. RAB3C can interact with RIMS2, RPH3A and RPH3AL.

Synonyms

Ras-related protein Rab-3C; RAB3C

Gene Name

RAB3C

Gene ID

115827

UniProt

Q96E17

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Rab3C, different from the related mouse and rat sequences by one amino acid.

Clonality

Polyclonal

Tissue Specificity

Expressed in brain, placenta and lung. .

Applications

Flow Cytometry

Field of Research

G Protein Signaling, Protein Trafficking, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins, Vesicle Transport

Purification

Immunogen affinity purified.

Form

Liquid

Function

Protein transport. Probably involved in vesicular traffic (By similarity) . .

References & Citations

1. Cheng H, Ma Y, Ni X, Jiang M, Luo Y, Ying K, Xie Y, Ma Y (Sep 2002) . Cloning, mapping, and characterization of the human Rab3C gene. Biochem Genet 40 (7–8) : 263–272. 2. Entrez Gene: RAB3C RAB3C, member RAS oncogene family

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

25952 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Ras-related protein Rab-3C

Subcellular Location

Cell membrane ; Lipid-anchor ; Cytoplasmic side .

Sequence Similarities

Belongs to the beta-catenin family.

Protein Name

Ras-related protein Rab-3C

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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