Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Connexin 45/GJA7/GJC1 Antibody Picoband®

Selected Variant

PA2206

Size: 100 µg/Vial

Boster Bio Anti-Connexin 45/GJA7/GJC1 Antibody catalog # PA2206. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Gap junction gamma-1 protein (GJC1), also known as gap junction alpha-7 protein (GJA7) or connexin 45 (Cx45), is a protein that in humans is encoded by the GJC1 gene. The International Radiation Hybrid Mapping Consortium mapped the GJA7 gene to chromosome 17q21.31. This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell.

Synonyms

Gap junction gamma-1 protein; Connexin-45; Cx45; Gap junction alpha-7 protein; GJC1; GJA7

Gene Name

GJC1

Gene ID

10052

UniProt

P36383

Host

Rabbit

Reactivity

Rat, Mouse, Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Connexin 45, different from the related mouse and rat sequences by one amino acid.

Clonality

Polyclonal

Tissue Specificity

Brain, liver, placenta, lymphocytes and erythrocytes.

Applications

WB

Field of Research

Cell Adhesion, Cytoskeleton/ECM, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

References & Citations

1. Kaba, R. A., Coppen, S. R., Dupont, E., Skepper, J. N., Elneil, S., Haw, M. P., Pepper, J. R., Yacoub, M. H., Rothery, S., Severs, N. J. Comparison of connexin 43, 40 and 45 expression patterns in the developing human and mouse hearts. Cell Commun. Adhesion 8: 339-343, 2001. 2. Tsai, M.-Y., Lan, K.-C., Huang, K.-E., Huang, F.-J., Kung, F.-T., Chang, S.-Y. Significance of mRNA levels of connexin37, connexin43, and connexin45 in luteinized granulosa cells of controlled hyperstimulated follicles. Fertil. Steril. 80: 1437-1443, 2003.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

45470 MW

Observed Molecular Weight

53 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Gap junction gamma-1 protein

Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Sequence Similarities

Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family.

Protein Name

Gap junction gamma-1 protein

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CD31 / PECAM-1 (Endothelial Cell Marker) (C31/2876R), CF647 conjugate, 0.1mg/mL
BNC472876-500 1x 500 µL

CD31 / PECAM-1 (Endothelial Cell Marker) (C31/2876R), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Anti-SNAP23 Antibody Picoband®
A02487 100 µg/Vial

Anti-SNAP23 Antibody Picoband®

Sign In for Pricing
View Details
P57 / KIP2 (KP10 + KIP2/880), CF405S conjugate, 0.1mg/mL
BNC041015-500 1x 500 µL

P57 / KIP2 (KP10 + KIP2/880), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD45RB (B-Cell Marker) (PTPRC/1783R), 0.2mg/mL
BNUB1783-500 1x 500 µL

CD45RB (B-Cell Marker) (PTPRC/1783R), 0.2mg/mL

Sign In for Pricing
View Details
Anti-TTI2 Antibody Picoband®, Dylight550 Conjugate
A12943-1-Dylight550 100 µg

Anti-TTI2 Antibody Picoband®, Dylight550 Conjugate

Sign In for Pricing
View Details
CLEC9A (1F6), CF405S conjugate, 0.1mg/mL
BNC042209-100 1x 100 µL

CLEC9A (1F6), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details