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Anti-Cytochrome P450 2U1 CYP2U1 Antibody Picoband® Fluoro594 Conjugated

Selected Variant

PA2022-Fluoro594

Size: 100 µg/Vial

Product Specifications

Background

Vitamins

Synonyms

Cytochrome P450 2U1;1.14.14.1; CYP2U1

Gene Name

CYP2U1

Gene ID

113612

UniProt

Q7Z449

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human CYP2U1.

Clonality

Polyclonal

Tissue Specificity

Widely expressed with stronger expression in thymus, heart and cerebellum. .

Applications

Flow Cytometry

Field of Research

Cancer, Cardiovascular, Cytochromes, Fatty Acid Oxidation, Fatty Acids, Lipases, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathways, Metabolism, Mitochondrial Metabolism, Pathways and Processes, Redox Metabolism, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. .

References & Citations

1. Chuang, S. S., Helvig, C., Taimi, M., Ramshaw, H. A., Collop, A. H., Amad, M., White, J. A., Petkovich, M., Jones, G., Korczak, B. CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1) -hydroxylation of fatty acids. J. Biol. Chem. 279: 6305-6314, 2004. 2. Tesson, C., Nawara, M., Salih, M. A. M., Rossignol, R., Zaki, M. S., Al Balwi, M., Schule, R., Mignot, C., Obre, E., Bouhouche, A., Santorelli, F. M., Durand, C. M., and 30 others. Alteration of fatty-acid-metabolizing enzymes affects mitochondrial form and function in hereditary spastic paraplegia. Am. J. Hum. Genet. 91: 1051-1064, 2012.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

61987 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Cytochrome P450 2U1

Subcellular Location

Endoplasmic reticulum membrane ; Multi-pass membrane protein . Microsome membrane .

Sequence Similarities

Belongs to the G-protein coupled receptor 1 family.

Protein Name

Cytochrome P450 2U1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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