What sizes are available for Anti-Protein Wnt-2b Wnt2b Antibody Picoband® Fluoro647 Conjugated?

Anti-Protein Wnt-2b Wnt2b Antibody Picoband® Fluoro647 Conjugated is available in the following size(s): 100 µg/Vial.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Anti-Protein Wnt-2b Wnt2b Antibody Picoband® Fluoro647 Conjugated

Q: What is the catalog number for Anti-Protein Wnt-2b Wnt2b Antibody Picoband® Fluoro647 Conjugated?

The catalog number for Anti-Protein Wnt-2b Wnt2b Antibody Picoband® Fluoro647 Conjugated is PA1985-Fluoro647.

Selected Variant

PA1985-Fluoro647

Size: 100 µg/Vial

Product Specifications

Background

WNT2B (Wingless-Type MMTV Integration Site Family Member 2B), is a protein that in humans is encoded by the WNT2B gene. This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. Katoh et al. (1996) used fluorescence in situ hybridization to map the WNT13 gene to chromosome 1p13. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis.

Synonyms

Protein Wnt-2b; Protein Wnt-13; WNT2B; WNT13

Gene Name

WNT2B

Gene ID

7482

UniProt

Q93097

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Wnt2b, identical to the related rat and mouse sequences.

Clonality

Polyclonal

Tissue Specificity

Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidney. Isoform 2 is expressed in fetal brain, fetal lung, fetal kidney, caudate nucleus, testis and cancer cell lines.

Applications

Flow Cytometry

Field of Research

Cancer, Oncoproteins/Suppressors, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, Tumor Suppressors

Purification

Immunogen affinity purified.

Form

Liquid

Function

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis.

References & Citations

1. Katoh, M., Hirai, M., Sugimura, T., Terada, M. Cloning, expression and chromosomal localization of Wnt-13, a novel member of the Wnt gene family. Oncogene 13: 873-876, 1996. 2. Ober, E. A., Verkade, H., Field, H. A., Stainier, D. Y. R. Mesodermal Wnt2b signalling positively regulates liver specification. Nature 442: 688-691, 2006. 3. Wolda, S. L., Moon, R. T. Cloning and developmental expression in Xenopus laevis of seven additional members of the Wnt family. Oncogene 7: 1941-1947, 1992.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

43770 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

Gene Name Synonym

Protein Wnt-2b

Subcellular Location

Secreted, extracellular space, extracellular matrix.

Sequence Similarities

Belongs to the nuclear hormone receptor family. NR1 subfamily.

Protein Name

Protein Wnt-2b

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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