Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Protein Wnt-2b Wnt2b Antibody Picoband® Fluoro550 Conjugated

Selected Variant

PA1985-Fluoro550

Size: 100 µg/Vial

Product Specifications

Background

WNT2B (Wingless-Type MMTV Integration Site Family Member 2B), is a protein that in humans is encoded by the WNT2B gene. This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. Katoh et al. (1996) used fluorescence in situ hybridization to map the WNT13 gene to chromosome 1p13. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis.

Synonyms

Protein Wnt-2b; Protein Wnt-13; WNT2B; WNT13

Gene Name

WNT2B

Gene ID

7482

UniProt

Q93097

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Wnt2b, identical to the related rat and mouse sequences.

Clonality

Polyclonal

Tissue Specificity

Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidney. Isoform 2 is expressed in fetal brain, fetal lung, fetal kidney, caudate nucleus, testis and cancer cell lines.

Applications

Flow Cytometry

Field of Research

Cancer, Oncoproteins/Suppressors, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, Tumor Suppressors

Purification

Immunogen affinity purified.

Form

Liquid

Function

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis.

References & Citations

1. Katoh, M., Hirai, M., Sugimura, T., Terada, M. Cloning, expression and chromosomal localization of Wnt-13, a novel member of the Wnt gene family. Oncogene 13: 873-876, 1996. 2. Ober, E. A., Verkade, H., Field, H. A., Stainier, D. Y. R. Mesodermal Wnt2b signalling positively regulates liver specification. Nature 442: 688-691, 2006. 3. Wolda, S. L., Moon, R. T. Cloning and developmental expression in Xenopus laevis of seven additional members of the Wnt family. Oncogene 7: 1941-1947, 1992.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

43770 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Protein Wnt-2b

Subcellular Location

Secreted, extracellular space, extracellular matrix.

Sequence Similarities

Belongs to the nuclear hormone receptor family. NR1 subfamily.

Protein Name

Protein Wnt-2b

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

IL-10RB Rabbit Polyclonal Antibody
HA500322 100 µL

IL-10RB Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Anti-SLC25A39 Antibody Picoband®
A14204-1-carrier-free 100 µg/Vial

Anti-SLC25A39 Antibody Picoband®

Sign In for Pricing
View Details
C-Myc (MYC909), CF488A conjugate, 0.1mg/mL
BNC880909-100 1x 100 µL

C-Myc (MYC909), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD44 Standard (156-3C11), 0.2mg/mL
BNUB0460-100 1x 100 µL

CD44 Standard (156-3C11), 0.2mg/mL

Sign In for Pricing
View Details