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Anti-Lamin B2/LMNB2 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Common model organisms

Synonyms

Lamin-B2; LMNB2; LMN2

Gene Name

LMNB2

Gene ID

84823

UniProt

Q03252

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Lamin B2, identical to the related rat and mouse sequences.

Clonality

Polyclonal

Tissue Specificity

Lung, testis and peripheral blood mononuclear cells.

Applications

Flow Cytometry

Field of Research

Apoptosis, Cancer, Cell Biology, Cell Death, Chromosome Structure, Cytoskeleton, Cytoskeleton/ECM, Epigenetics and Nuclear Signaling, Intermediate Filaments, Nucleus, Signal Transduction, Subcellular Markers, Tags & Cell Markers

Purification

Immunogen affinity purified.

Form

Liquid

Function

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.

References & Citations

1. Biamonti, G., Giacca, M., Perini, G., Contreas, G., Zentilin, L., Weighardt, F., Guerra, M., Della Valle, G., Saccone, S., Riva, S., Falaschi, A. The gene for a novel human lamin maps at a highly transcribed locus of chromosome 19 which replicates at the onset of S-phase. Molec. Cell. Biol. 2. Giacca, M., Zentilin, L., Norio, P., Diviacco, S., Dimitrova, D., Contreas, G., Biamonti, G., Perini, G., Weighardt, F., Riva, S., Falaschi, A. Fine mapping of a replication origin of human DNA. Proc. Nat. Acad. Sci. 91: 7119-7123, 1994.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

67689 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Lamin-B2

Subcellular Location

Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.

Sequence Similarities

Belongs to the intermediate filament family.

Protein Name

Lamin-B2

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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