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Anti-Homeobox protein Hox-A6 HOXA6 Antibody Picoband® Fluoro488 Conjugated

Selected Variant

PA1605-Fluoro488

Size: 100 µg/Vial

Product Specifications

Background

HOXA6 (HOMEOBOX A6), also known as HOX1B, MOUSE or HOMOLOG OF, is a protein that in humans is encoded by the HOXA6 gene, which is also part of the A cluster on chromosome 7. HOXA6 encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Its cytogenetic location is 7q15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.

Synonyms

Homeobox protein Hox-A6; Homeobox protein Hox-1B; HOXA6; HOX1B

Gene Name

HOXA6

Gene ID

3203

UniProt

P31267

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human HOXA6, identical to the related rat and mouse sequences.

Clonality

Polyclonal

Tissue Specificity

Embryonic nervous system.

Applications

Flow Cytometry

Field of Research

Transcription, Transcription Factors

Purification

Immunogen affinity purified.

Form

Liquid

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

References & Citations

1. Acampora, D., D'Esposito, M., Faiella, A., Pannese, M., Migliaccio, E., Morelli, F., Stornaiuolo, A., Nigro, V., Simeone, A., Boncinelli, E. The human HOX gene family. Nucleic Acids Res. 17: 10385-10402, 1989. 2. Balling, R., Mutter, G., Gruss, P., Kessel, M. Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox-1.1 in transgenic mice. Cell 58: 337-347, 1989. 3. McAlpine PJ, Shows TB (Aug 1990) . Nomenclature for human homeobox genes.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

26339 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Homeobox protein Hox-A6

Subcellular Location

Nucleus.

Sequence Similarities

Belongs to the Antp homeobox family.

Protein Name

Homeobox protein Hox-A6

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

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