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Anti-Interleukin-13 IL13 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Interleukin 13

Synonyms

Interleukin-13; IL-13; T-cell activation protein P600; Il13; Il-13

Gene Name

IL13

Gene ID

116553

UniProt

P42203

Host

Rabbit

Reactivity

Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of rat IL-13.

Clonality

Polyclonal

Applications

Flow Cytometry

Field of Research

Cytokines, Immunology, Innate Immunity, Interleukins

Purification

Immunogen affinity purified.

Form

Liquid

Function

Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (By similarity) . .

References & Citations

1. Blackburn, M. R., Lee, C. G., Young, H. W. J., Zhu, Z., Chunn, J. L., Kang, M. J., Banerjee, S. K., Elias, J. A.Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. 2. Paul, W. E.Personal Communication.Bethesda, Md. 3/6/1993. 3. Punnonen, J., Aversa, G., Cocks, B. G., McKenzie, A. N. J., Menon, S., Zurawski, G., de Waal Malefyt, R., de Vries, J. E.Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.Proc. Nat. Acad. Sci. 90: 3730-3734, 1993.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

14093 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Interleukin-13

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the type I cytokine receptor family. Type 3 subfamily.

Protein Name

Interleukin-13 (IL-13)

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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