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Anti-Carbonic Anhydrase I/CA1 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Carbonic anhydrase 1 is an enzyme that in humans is encoded by the CA1 gene. It is a member of the Carbonic anhydrase. The CA1 gene is mapped to 8q22. CAI has got about 260 amino acids. This protein is highly expressed in erythrocytes. As catalysts of the reversible hydration of carbon dioxide, CAI participate in a variety of biologic processes like respiration, calcification, acid-base balance etc.

Synonyms

Carbonic anhydrase 1;4.2.1.1; Carbonate dehydratase I; Carbonic anhydrase B; CAB; Carbonic anhydrase I; CA-I; CA1

Gene Name

CA1

Gene ID

759

UniProt

P00915

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Carbonic Anhydrase I, different from the mouse sequence by one amino acid.

Clonality

Polyclonal

Applications

Flow Cytometry

Field of Research

Neuroscience, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea. .

References & Citations

1. Lowe N, Edwards YH, Edwards M, Butterworth PH (Nov 1991) . Physical mapping of the human carbonic anhydrase gene cluster on chromosome 8. Genomics 10 (4) : 882–8. 2. Entrez Gene: CA1 carbonic anhydrase I.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

28870 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Carbonic anhydrase 1

Subcellular Location

Cytoplasm.

Sequence Similarities

Belongs to the IL-4/IL-13 family.

Protein Name

Carbonic anhydrase 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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