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Anti-Apolipoprotein D/APOD Antibody Picoband®

Boster Bio Anti-Apolipoprotein D/APOD Antibody catalog # PA1388. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Apolipoprotein D (Apo-D) is a protein that in humans, encoded by the APOD gene. Being a member of the alpha (2 mu) -microglobulin superfamily of carrier proteins, Apo-D is also known as lipocalin.The gene has been localized to the p14.2----qter region of human chromosome 3. It is a glycoprotein of estimated molecular weight 33,000 Da. The Apo-D encoded a protein of 169 amino acid residue.It has been detected in human liver, intestine, pancreas, kidney, placenta, adrenal, spleen, and fetal brain tissue. For its features, Apo-D has been a biomarker of androgen insensitivity syndrome (AIS) .

Synonyms

Apolipoprotein D; Apo-D; ApoD; APOD

Gene Name

APOD

Gene ID

347

UniProt

P05090

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Apolipoprotein D.

Clonality

Polyclonal

Tissue Specificity

Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.

Applications

WB

Field of Research

Growth Factors/Hormones, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

APOD occurs in the macromolecular complex with lecithin- cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.

References & Citations

1. Drayna, D. T., McLean, J. W., Wion, K. L., Trent, J. M., Drabkin, H. A., Lawn, R. M. Human apolipoprotein D gene: gene sequence, chromosome localization, and homology to the alpha-2mu-globulin superfamily. DNA 6: 199-204, 1987. 2. Drayna, D., Fielding, C., McLean, J., Baer, B., Castro, G., Chen, E., Comstock, L., Henzel, W., Kohr, W., Rhee, L., Wion, K., Lawn, R.Cloning and expression of human apolipoprotein D cDNA.J. Biol. Chem.261: 16535-16539, 1986. 3. Appari M, Werner R, Wünsch L, Cario G, Demeter J, Hiort O, Riepe F, Brooks JD, Holterhus PM (June 2009) . Apolipoprotein D (APOD) is a putative biomarker of androgen receptor function in androgen insensitivity syndrome. J. Mol. Med. 87 (6) : 623–32.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

21276 MW

Observed Molecular Weight

30 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Apolipoprotein D

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein Name

Apolipoprotein D (Apo-D/ApoD)

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

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