Anti-Matrix metalloproteinase-9 MMP9 Antibody Picoband® Fluoro647 Conjugated
Selected Variant
PA1357-Fluoro647
Size: 100 µg/Vial
Product Specifications
Background
Matrix metallopeptidase 9
Synonyms
Matrix metalloproteinase-9; MMP-9;3.4.24.35;92 kDa gelatinase;92 kDa type IV collagenase; Gelatinase B; GELB;67 kDa matrix metalloproteinase-9;82 kDa matrix metalloproteinase-9; MMP9; CLG4B
Gene Name
MMP9
Gene ID
4318
UniProt
P14780
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human MMP-9, different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.
Clonality
Polyclonal
Tissue Specificity
Produced by normal alveolar macrophages and granulocytes.
Applications
Flow Cytometry
Field of Research
Angiogenesis, Atherosclerosis, Cancer, Cardiovascular, Cell Biology, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Metalloprotease, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction, Tumor Biomarkers
Purification
Immunogen affinity purified.
Form
Liquid
Function
May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. .
References & Citations
1. Template:, 92kDa type IV collagenase) 2. Yuichiro Hirose et al. (May 2008) . A Functional Polymorphism in THBS2 that Affects Alternative Splicing and MMP Binding Is Associated with Lumbar-Disc Herniation.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
78458 MW
Specificity
No cross reactivity with other proteins.
Applications Notes
6
Gene Name Synonym
Matrix metalloproteinase-9
Subcellular Location
Secreted, extracellular space, extracellular matrix .
Sequence Similarities
Belongs to the peptidase M10A family.
Protein Name
Matrix metalloproteinase-9 (MMP-9)
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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