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Anti-Ly6al Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Ly6al, lymphocyte antigen 6 complex, locus A-like, is also known as ?Ly6a, Ly6a_predicted.

Synonyms

Ly6al

Gene Name

Ly6al

Gene ID

0

UniProt

D3ZPQ1

Host

Rabbit

Reactivity

Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of rat Ly6al.

Clonality

Polyclonal

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, Cardiogenesis, Cardiovascular, Developmental Biology, Hematopoietic Progenitors, Immunology, Lineage Markers, Lineage Specification, Non-CD, Organogenesis, Stem Cells, Surface Molecules, T Cells

Purification

Immunogen affinity purified.

Form

Liquid

Function

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3) ; this then triggers calcium ion release into the cytosol. .

References & Citations

http://www.uniprot.org/uniprot/D3ZPQ1 http://www.ncbi.nlm.nih.gov/gene/362935

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

51715 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Lymphocyte antigen 6 complex, locus A-like

Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Phosphorylation in response to agonist binding promotes receptor internalization. .

Protein Name

Ly6-A antigen

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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