Anti-Ly6al Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Ly6al, lymphocyte antigen 6 complex, locus A-like, is also known as ?Ly6a, Ly6a_predicted.
Synonyms
Ly6al
Gene Name
Ly6al
Gene ID
0
UniProt
D3ZPQ1
Host
Rabbit
Reactivity
Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of rat Ly6al.
Clonality
Polyclonal
Applications
Flow Cytometry
Field of Research
Adaptive Immunity, Cardiogenesis, Cardiovascular, Developmental Biology, Hematopoietic Progenitors, Immunology, Lineage Markers, Lineage Specification, Non-CD, Organogenesis, Stem Cells, Surface Molecules, T Cells
Purification
Immunogen affinity purified.
Form
Liquid
Function
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3) ; this then triggers calcium ion release into the cytosol. .
References & Citations
http://www.uniprot.org/uniprot/D3ZPQ1 http://www.ncbi.nlm.nih.gov/gene/362935
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
51715 MW
Specificity
No cross reactivity with other proteins.
Applications Notes
6
Gene Name Synonym
Lymphocyte antigen 6 complex, locus A-like
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Phosphorylation in response to agonist binding promotes receptor internalization. .
Protein Name
Ly6-A antigen
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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