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Anti-Neurotrophin 3/NTF3 Antibody Picoband® Fluoro550 Conjugated

Selected Variant

PA1062-Fluoro550

Size: 100 µg/Vial

Product Specifications

Background

Neurotrophin-3 is a member of a family of neurotrophic factors, that is closely related to both nerve growth factor and brain derived neurotrophic factor. These proteins are involved in the maintenance of the adult nervous system and affect development of neurons in the embryo when it is expressed in human placenta. NT3 deficient mice generated by gene targeting display severe movement defects of the limbs.

Synonyms

Neurotrophin-3; NT-3; HDNF; Nerve growth factor 2; NGF-2; Neurotrophic factor; NTF3

Gene Name

NTF3

Gene ID

4908

UniProt

P20783

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Neurotrophin 3, identical to the related rat and mouse sequences.

Clonality

Polyclonal

Tissue Specificity

Brain and peripheral tissues.

Applications

Flow Cytometry

Field of Research

Cancer, Cancer Metabolism, Carbohydrate Metabolism, Energy Metabolism, Energy Transfer Pathways, Epigenetics and Nuclear Signaling, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Of Carbohydrates, Pathways and Processes, Signal Transduction, Transcription, Tumor Biomarkers

Purification

Immunogen affinity purified.

Form

Liquid

Function

Seems to promote the survival of visceral and proprioceptive sensory neurons.

References & Citations

1. Jones, K. R.; Reichardt, L. F. : Molecular cloning of a human gene that is a member of the nerve growth factor family. Proc. Nat. Acad. Sci. 87: 8060-8064, 1990. 2. Rosenthal A., Goeddel D.V., Nguyen T., Lewis M., Shih A., Laramee G.R., Nikolics K., Winslow J.W.; Primary structure and biological activity of a novel human neurotrophic factor.; Neuron 4:767-773 (1990) .

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

29355 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Neurotrophin-3

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the enolase family.

Protein Name

Neurotrophin-3 (NT-3)

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

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