Anti-Calretinin/CALB2 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Calbindin is a calcium-binding protein belonging to the troponin C superfamily. Calretinin is expressed in central and peripheral nervous system and in many normal and pathological tissues. The rat and human calretinin exhibit 98% sequence homology and 91% homology to many other species. Two calcium binding proteins, calbindin and calretinin, have been reported to be expressed in abundance in Purkinje cells and other cell types in the cerebellum.

Synonyms

Calretinin; CR;29 kDa calbindin; CALB2; CAB29

Gene Name

CALB2

Gene ID

794

UniProt

P22676

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Calretinin, identical to the related rat sequence.

Clonality

Polyclonal

Tissue Specificity

Brain.

Applications

Flow Cytometry

Field of Research

Calcium Binding Proteins, Calcium Signaling, Neuroscience, Neurotransmission

Purification

Immunogen affinity purified.

Form

Liquid

Function

Calretinin is a calcium-binding protein which is abundant in auditory neurons.

References & Citations

1. Parmentier M.; The human calbindins: cDNA and gene cloning.; Adv. Exp. Med. Biol. 255:233-240 (1989) . 2. Strauss K.I., Kuznicki J., Winsky L., Kawagoe J.I., Hammer M., Jacobowitz D.M.; The mouse calretinin gene promoter region: structural and functional components.; Brain Res. Mol. Brain Res. 49:175-187 (1997) . 3. Gabrielides C., McCormack A.L., Hunt D.F., Christakos S.; Brain calbindin-D28k and an Mr 29,000 calcium binding protein in cerebellum are different but related proteins: evidence obtained from sequence analysis by tandem mass spectrometry.; Biochemistry 30:656-662 (1991) .

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

31540 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

Gene Name Synonym

Calretinin

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the calbindin family.

Protein Name

Calretinin (CR)

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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Anti-Calretinin/CALB2 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Form

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Specificity

Applications Notes

Gene Name Synonym

Subcellular Location

Sequence Similarities

Protein Name

Isotype

Contents

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