Anti-P-GlycoProtein (MDR) ABCB1 Antibody (Monoclonal, F4)
Boster Bio Anti-P-GlycoProtein (MDR) ABCB1 Antibody (Monoclonal, F4) catalog # MA1060. Tested in IHC, ICC, WB applications. This antibody reacts with Human.
Product Specifications
Background
Synonyms
Gene Name
Abcb1a
Gene ID
Human (5243), Mouse (18671), Rat (170913)
UniProt
P08183
Host
Mouse
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
Mixture of human and hamster drug-resistant whole cells and crude plasma membranes.
Clonality
Monoclonal
Clone
Clone: F4
Tissue Specificity
ABCB1: Expressed in liver, kidney, small intestineand brain.
Applications
IHC, ICC, WB
Field of Research
ATPases, Cancer, Lipid Metabolism, Metabolism, Nuclear Import/Export, Plasma Membrane, Protein Trafficking, Signal Transduction
Purification
Ascites
Concentration
Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.
Form
Lyophilized
Reconstitution
Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Function
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. .
References & Citations
Storage Conditions
Calculated Molecular Weight
140647 MW
Observed Molecular Weight
200 kDa
Specificity
No cross reactivity with other proteins.
Gene Name Synonym
DNA helicase
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Sequence Similarities
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
Protein Name
DNA replication licensing factor MCM7
Isotype
Mouse IgG1
Contents
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
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