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Anti-NOXO1 Antibody Picoband® APC Conjugated

Product Specifications

Background

This gene encodes an NADPH oxidase (NOX) organizer, which positively regulates NOX1 and NOX3. The protein contains a PX domain and two SH3 domains. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms

NOXO1; P41NOX; SH3PXD5; NADPH oxidase organizer 1; NADPH oxidase regulatory protein; Nox organizer 1; Nox-organizing protein 1; SH3 and PX domain-containing protein 5

Gene Name

NOXO1

Gene ID

124056

UniProt

Q8NFA2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human NOXO1 recombinant protein (Position: M1-E294) . Human NOXO1 shares 71.1% amino acid (aa) sequence identity with mouse NOXO1.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Banfi, B., Clark, R. A., Steger, K., Krause, K.-H. Two novel proteins activate superoxide generation by the NADPH oxidase NOX1. J. Biol. Chem. 278: 3510-3513, 2003. 2. Cheng, G., Lambeth, J. D. NOXO1, regulation of lipid binding, localization, and activation of Nox1 by the Phox homology (PX) domain. J. Biol. Chem. 279: 4737-4742, 2004. 3. Cheng, G., Lambeth, J. D. Alternative mRNA splice forms of NOXO1: differential tissue expression and regulation of Nox1 and Nox3. Gene 356: 118-126, 2005.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

41 kDa

Applications Notes

6

Gene Name Synonym

NADPH oxidase organizer 1

Protein Name

NADPH oxidase organizer 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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