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Anti-Gankyrin/PSMD10 Antibody Picoband®

Boster Bio Anti-Gankyrin/PSMD10 Antibody Picoband® catalog # A03169-2. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.

Synonyms

PSMD10; 26S proteasome non-ATPase regulatory subunit 10; 26S proteasome regulatory subunit p28; Gankyrin; p28 (GANK

Gene Name

PSMD10

Gene ID

5716

UniProt

O75832

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human Gankyrin/PSMD10 recombinant protein (Position: M1-G226) . Human Gankyrin/PSMD10 shares 94.2% and 94.7% amino acid (aa) sequence identity with mouse and rat Gankyrin/PSMD10, respectively.

Clonality

Polyclonal

Applications

WB, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Dong, L., Yang, G., Pan, Y., Chen, Y., Tan, Y., Dai, R., Ren, Y., Fu, J., Wang, H. The oncoprotein p28 (GANK) establishes a positive feedback loop in beta-catenin signaling. Cell Res. 21: 1248-1261, 2011. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 9/26/2012. 3. Hori, T., Kato, S., Saeki, M., DeMartino, G. N., Slaughter, C. A., Takeuchi, J., Toh-e, A., Tanaka, K. cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome. Gene 216: 113-122, 1998.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

24 kDa

Observed Molecular Weight

24 kDa

Applications Notes

6

Gene Name Synonym

Proteasome 26S subunit, non-ATPase 10

Protein Name

26S proteasome non-ATPase regulatory subunit 10

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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