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Anti-PRDM6 Antibody Picoband®

Boster Bio Anti-PRDM6 Antibody Picoband® catalog # A13216-1. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

The protein encoded by this gene is a transcriptional repressor and a member of the PRDM family. Family members contain a PR domain and multiple zinc-finger domains. The encoded protein is involved in regulation of vascular smooth muscle cells (VSMC) contractile proteins. Mutations in this gene result in patent ductus arteriosus 3 (PDA3) .

Synonyms

PRDM6; PFM3; Putative histone-lysine N-methyltransferase PRDM6; EC 2.1.1.-; PR domain zinc finger protein 6; PR domain-containing protein 6

Gene Name

PRDM6

Gene ID

93166

UniProt

Q9NQX0

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human PRDM6 recombinant protein (Position: R165-R452) . Human PRDM6 shares 97.2% amino acid (aa) sequence identity with mouse PRDM6.

Clonality

Polyclonal

Applications

WB, ICC/IF, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 6/16/2016. 2. Li, N., Subrahmanyan, L., Smith, E., Yu, X., Zaidi, S., Choi, M., Mane, S., Nelson-Williams, C., Behjati, M., Kazemi, M., Hashemi, M., Fathzadeh, M., and 12 others. Mutations in the histone modifier PRDM6 are associated with isolated nonsyndromic patent ductus arteriosus. Am. J. Hum. Genet. 98: 1082-1091, 2016. Note: Erratum: Am. J. Hum. Genet. 99: 1000 only, 2016. 3. Lynch, H. T., Grissom, R. L., Magnuson, C. R., Krush, A. Patent ductus arteriosus: study of two families. JAMA 194: 135-118, 1965.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

61 kDa

Observed Molecular Weight

61 kDa

Applications Notes

6

Gene Name Synonym

PR/SET domain 6

Protein Name

Putative histone-lysine N-methyltransferase PRDM6

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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