Anti-IER3 Antibody Picoband® APC Conjugated

This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein.

IER3; DIF2; IEX1; PRG1; Radiation-inducible immediate-early gene IEX-1; Differentiation-dependent gene 2 protein; Protein DIF-2; Immediate early protein GLY96; Immediate early response 3 protein; PACAP-responsive gene 1 protein; Protein PRG1

A synthetic peptide corresponding to a sequence at the C-terminus of human IER3. Human IER3 shares 85% amino acid (aa) sequence identity with mouse IER3.

1. Akilov, O. E., Ustyugova, I. V., Zhi, L., Hasan, T., Wu, M. X. Enhanced susceptibility to Leishmania infection in resistant mice in the absence of immediate early response gene X-1. J. Immun. 183: 7994-8003, 2009. 2. Charles, C. H., Yoon, J. K., Simske, J. S., Lau, L. F. Genomic structure, cDNA sequence, and expression of gly96, a growth factor-inducible immediate-early gene encoding a short-lived glycosylated protein. Oncogene 8: 797-801, 1993. 3. Kondratyev, A. D., Chung, K.-N., Jung, M. O. Identification and characterization of a radiation-inducible glycosylated human early-response gene. Cancer Res. 56: 1498-1502, 1996.