Anti-SCAI Antibody Picoband® PE Conjugated
Product Specifications
Background
This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A) -Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described.
Synonyms
SCAI; C9orf126; Protein SCAI; Suppressor of cancer cell invasion protein
Gene Name
SCAI
Gene ID
286205
UniProt
Q8N9R8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SCAI recombinant protein (Position: M1-A549) . Human SCAI shares 98.2% amino acid (aa) sequence identity with mouse SCAI.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Brandt, D. T., Baarlink, C., Kitzing, T. M., Kremmer, E., Ivaska, J., Nollau, P., Grosse, R. SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta-1-integrin. Nature Cell Biol. 11: 557-567, 2009. 2. Fintha, A., Gasparics, A., Fang, L., Erdei, Z., Hamar, P., Mozes, M. M., Kokeny, G., Rosivall, L., Sebe, A. Characterization and role of SCAI during renal fibrosis and epithelial-to-mesenchymal transition. Am. J. Path. 182: 388-400, 2013. 3. Gross, M. B. Personal Communication. Baltimore, Md. 3/4/2021.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
70 kDa
Applications Notes
6
Gene Name Synonym
Suppressor of cancer cell invasion
Protein Name
Protein SCAI
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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