Anti-SCAI Antibody Picoband® Biotin Conjugated
Product Specifications
Background
This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A) -Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described.
Synonyms
SCAI; C9orf126; Protein SCAI; Suppressor of cancer cell invasion protein
Gene Name
SCAI
Gene ID
286205
UniProt
Q8N9R8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SCAI recombinant protein (Position: M1-A549) . Human SCAI shares 98.2% amino acid (aa) sequence identity with mouse SCAI.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Brandt, D. T., Baarlink, C., Kitzing, T. M., Kremmer, E., Ivaska, J., Nollau, P., Grosse, R. SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta-1-integrin. Nature Cell Biol. 11: 557-567, 2009. 2. Fintha, A., Gasparics, A., Fang, L., Erdei, Z., Hamar, P., Mozes, M. M., Kokeny, G., Rosivall, L., Sebe, A. Characterization and role of SCAI during renal fibrosis and epithelial-to-mesenchymal transition. Am. J. Path. 182: 388-400, 2013. 3. Gross, M. B. Personal Communication. Baltimore, Md. 3/4/2021.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
70 kDa
Gene Name Synonym
Suppressor of cancer cell invasion
Protein Name
Protein SCAI
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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