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Anti-C6orf130/OARD1 Antibody Picoband® HRP Conjugated

Product Specifications

Background

The protein encoded by this gene is a deacylase that can convert O-acetyl-ADP-ribose to ADP-ribose and acetate, O-propionyl-ADP-ribose to ADP-ribose and propionate, and O-butyryl-ADP-ribose to ADP-ribose and butyrate. The ADP-ribose product is able to inhibit these reactions through a competitive feedback loop.

Synonyms

OARD1; C6orf130; TARG1; ADP-ribose glycohydrolase OARD1; O-acetyl-ADP-ribose deacetylase 1; EC 3.5.1.-; Terminal ADP-ribose protein glycohydrolase 1; [Protein ADP-ribosylglutamate] hydrolase OARD1; EC 3.2.2.-

Gene Name

OARD1

Gene ID

221443

UniProt

Q9Y530

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human C6orf130/OARD1 recombinant protein (Position: M1-L152) . Human C6orf130/OARD1 shares 95.4% amino acid (aa) sequence identity with mouse C6orf130/OARD1.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 12/6/2011. 2. Peterson, F. C., Chen, D., Lytle, B. L., Rossi, M. N., Ahel, I., Denu, J. M., Volkman, B. F. Orphan macrodomain protein (human C6orf130) is an O-acyl-ADP-ribose deacylase: solution structure and catalytic properties. J. Biol. Chem. 286: 35955-35965, 2011.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

17 kDa

Gene Name Synonym

O-acyl-ADP-ribose deacylase 1

Protein Name

ADP-ribose glycohydrolase OARD1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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