Anti-WDR37 Antibody Picoband® Biotin Conjugated

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.

1. Kanca, O., Andrews, J. C., Lee, P.-T., Patel, C., Braddock, S. R., Slavotinek, A. M., Cohen, J. S., Gubbels, C. S., Aldinger, K. A., Williams, J., Indaram, M., Fatemi, A., and 16 others. De novo variants in WDR37 are associated with epilepsy, colobomas, dysmorphism, developmental delay, intellectual disability, and cerebellar hypoplasia. Am. J. Hum. Genet. 105: 413-424, 2019. Note: Erratum: Am. J. Hum. Genet. 105: 672-674, 2019. 2. Reis, L. M., Sorokina, E. A., Thompson, S., Muheisen, S., Velinov, M., Zamora, C., Aylsworth, A. S., Semina, E. V. De novo missense variants in WDR37 cause a severe multisystemic syndrome. Am. J. Hum. Genet. 105: 425-433, 2019. 3. Stumpf, A. M. Personal Communication. Baltimore, Md. 09/25/2019.